Following the announcement of Sofia Vergara and Joe Manganiello's divorce, Vergara's "Modern Family" co-star, Julie Bowen, offered a supportive comment on Vergara's Instagram post. The post, captioned "final days of vacay," featured Vergara in a blue leopard-print bikini. Bowen's comment, "This is what single and [fire emoji] looks like!!!", quickly garnered attention.

Vergara and Manganiello confirmed their separation after seven years of marriage in a joint statement, requesting privacy as they navigate this new chapter. The divorce news came shortly after Vergara's birthday, which Manganiello acknowledged on Instagram, despite his absence from her recent vacation photos. The couple initially met at the 2014 White House Correspondents’ Dinner and were later introduced by another "Modern Family" co-star, Jesse Tyler Ferguson.

In a 2019 interview, Manganiello expressed his deep affection for Vergara, emphasizing their compatibility and shared laughter. He described making his wife laugh until she cried as his "favorite thing in the world."